Adapted from Flannery DD, Puopolo KM. Neonatal Antibiotic Use: What Are We Doing and Where Shall We Go? Neoreviews. 2018;19(9):e516-e5251
Morbidity and mortality associated with antibiotic exposure: Multiple studies suggest that antibiotics carry potential risks for preterm infants treated for culture-negative infections (or treated for infections without culture-confirmation).