Obtaining and tracking data is essential in establishing an effective ASP.
Antibiotic Use Data
Days of therapy (DOT) per 1,000 patient days or 1,000 days present
Overall and for specific agents or groups of agents. DOT includes the cumulative days of therapy of each antibiotic. For example, if a patient received vancomycin and cefepime for 2 days, the DOT would be 4 (2 drugs x 2 days).
Length of therapy (LOT) per 1,000 patient days or 1,000 days present
Overall and for specific agents or groups of agents. LOT includes the total duration of therapy of any antibiotic therapy. For example, if a patient received vancomycin and cefepime for 2 days, the LOT would be 2.
Denominator — patient days versus days present
Patient days are determined based on hospital census data captured each day at a specific time. Therefore, if you have a patient in the hospital Monday through Wednesday and the daily census is captured at midnight the number of patient days would be 2. If the patient received an antibiotic on all 3 days then the DOT would be 3.
Days present accounts for any time that the patient is present in the hospital. This data can be obtained from electronic health records through their admission, discharge and transfer data. Therefore, if a patient is in the hospital Monday through Wednesday, the days present is 3.