Cincinnati Children’s Hospital Medical Center

TRAINING PROGRAM DIRECTOR: Grant Paulsen, MD

COORDINATOR:  Amy Jensen

CHIEF, INFECTIOUS DISEASES: Lara Danziger-Isakov, MD, MPH

MAJOR FEATURES OF TRAINING PROGRAM: The mission of our fellowship program is to prepare Pediatric Infectious Diseases trainees for successful careers in academic medicine as outstanding clinicians, researchers, and educators. We seek to do this by fostering the development of clinical expertise through exposure to a wide variety of common and uncommon infections in normal and immunocompromised hosts. Opportunities for clinical training include both a general and immunocompromised consult service as well as out-patient clinics in general ID, immunocompromised host infections, an International Adoption Program and HIV care.

Development of expertise in a scholarly area applicable to infectious diseases will take place during the entire fellowship primarily through mentor-guided development and execution of a longitudinal research project. The Infectious Diseases Division offers outstanding training opportunities in basic, translational and clinical research. Opportunities to pursue MPH as well as master’s degrees in programs such as clinical trials, epidemiology, education or immunology are available.

Our 3-year ACGME-approved program is especially known for its emphasis in transplant infectious diseases, vaccine development, basic virology and immunology research, epidemiologic research, and antimicrobial stewardship. An additional fourth year of training is also available for appropriate candidates interested in pursuing further training in academic research and/or care of immunocompromised patients.

TITLE(S) OF RECENT FELLOWS’ PUBLISHED RESEARCH PAPERS:

1. Murphy M, Chamberlain A, Tang P, Turpin B, Danziger-Isakov L. Paediatric ganciclovir dosing in extracorporeal membrane oxygenation: Is standard dosing good enough? J Clin Pharm Ther. 2020; 45: 218– 220. https://doi.org/10.1111/jcpt.13051. PMID: 31545518.
2. Pangonis S, et al. Evaluation of a change in cytomegalovirus prevention strategy following pediatric solid organ transplantation. Transpl Infect Dis. 2020 Apr; 22(2):e13232. PMID: 31840369.
3. Miller-Handley H, Luckett K, Govil A. Treatment options for Coronavirus Disease 2019 in Patients with Reduced or Absent Kidney Function. Adv Chronic Kidney Dis. 2020 Sep:27(5):434-441. PMID: 33308510.
4. Prasanphanich NS, Gregory E, Erickson J, Miller-Handley H, Kinder J, Way SS. Preconceptual Priming Overrides Susceptibility to Escherichia coli Systemic Infection during Pregnancy. mBio. 2021 Feb 23;12(1):e00002-21. PMID: 33622714.
5. Miller-Handley H, Paulsen G, Hooper D, Lake M, Lazear D, Danziger-Isakov L. Durability of the hepatitis B vaccination in pediatric renal transplant recipients. Clin Transplant 2018 May;32(5):e13247. PMID: 29603431.

GRANT FUNDING RECEIVED FOR FELLOW RESEARCH PROJECTS:

1. NIH T32 Vaccinology Training Program (5T32AI65396-03). 3 fellows. 2022-2027
2. NIH T32 Pediatric Clinical Pharmacology (5T32HD069054-10). 1 fellow. 2019-2021.
3. NIH K12 Pediatric Scientist Development Program (PSDP). 2 fellows. 2021-2023.
4. Thrasher Early Career Award. 1 fellow. 2021

AFFILIATED HOSPITAL(S):

1. Cincinnati Children’s Hospital Medical Center
2. University of Cincinnati Medical Center
3. Good Samaritan Hospital

FELLOWS ACCEPTED EACH YEAR:  2

FUNDING IS ENSURED FOR ALL 3 YEARS:  Yes

NUMBER OF INPATIENT/OUTPATIENT CONSULTS PER YEAR:  1,400

VISAS ACCEPTED: J1, H1b

IS COMPLETION OF PEDIATRIC RESIDENCY TRAINING IN THE U.S. OR CANADA A REQUIREMENT? Yes

Program provides training (didactic lectures, hands on experience, or antimicrobial stewardship meetings/membership in:

1. Microbiology lab on site
2. Infection control and hospital epidemiology
3. Antimicrobial stewardship
4. Immunocompromised hosts

Opportunity to fulfill the ABP requirements for scholarly activity is available in the following general areas:

1. Antimicrobial agents
2. Antimicrobial stewardship
3. Bacteriology/bacterial infections
4. Bioethics
5. Clinical trials
6. Epidemiology and statistics
7. Global health
8. HIV
9. Immunizations
10. Infection control/hospital epidemiology
11. Medical education
12. Mycology/fungal infections
13. Public health
14. Quality improvement
15. Transplant medicine
16. Virology/viral diseases

Opportunities for research outside of the ID Division?  Yes

Program offers the opportunity to obtain a Master’s degree in a field such as Public Health, Education, Clinical Sciences or Epidemiology (assuming appropriate arrangements are made):  Yes