TRAINING PROGRAM DIRECTOR: Pia S. Pannaraj, MD, MPH (Associate Professor)
RESEARCH INTEREST: Vaccines and Vaccine-preventable diseases, Maternal Immunizations, Gut microbiome in the developing infant, Breast milk microbiome, Global health education
CHIEF OF INFECTIOUS DISEASES: Michael Neely, MD (Associate Professor)
RESEARCH INTEREST: Personalized medicine and optimal dosing of antimicrobial agents and other therapeutic drugs; Anti-bacterial, anti-viral and anti-fungal pharmacology, Pediatric clinical pharmacology; Pediatric drug development.
Michael Smit, MD, MSPH (Assistant Professor)
RESEARCH INTERESTS: Emerging infectious disease epidemiology, Ebola virus disease, Infection control, Pandemic response preparation, Medical education in low-resource settings, and tropical medicine
TITLE(S) OF RECENT FELLOWS’ PUBLISHED PAPERS OF RESEARCH PROJECTS:
The Brief Case: Neonatal Meningitis Caused by Listeria monocytogenes Diagnosed by Multiplex Molecular Panel.
Anand V, Holmen J, Neely M, Pannaraj PS, Dien Bard J.
J Clin Microbiol. 2016 Dec;54(12):2846-2849. PMID: 27881634
Influenza Vaccine is Protective Against Laboratory-confirmed Influenza in Obese Children.
Smit MA, Wang HL, Kim E, Barragan N, Aldrovandi GM, Nelson El Amin A, Mascola L, Pannaraj PS.
Pediatr Infect Dis J. 2016 Apr;35(4):440-5. doi: 10.1097/INF.0000000000001029.
Pediatric carbapenem-resistant Enterobacteriaceae in Los Angeles, California, a high-prevalence region in the United States.
Pannaraj PS, Bard JD, Cerini C, Weissman SJ.
Pediatr Infect Dis J. 2015 Jan;34(1):11-6. doi: 10.1097/INF.0000000000000471.
Clinical and microbiologic outcomes of quinolone prophylaxis in children with acute myeloid leukemia.
Felsenstein S, Orgel E, Rushing T, Fu C, Hoffman JA.
Pediatr Infect Dis J. 2015 Apr;34(4):e78-84. doi: 10.1097/INF.0000000000000591. PMID: 25764103
Molecular and clinical diagnosis of group A streptococcal pharyngitis in children.
Felsenstein S, Faddoul D, Sposto R, Batoon K, Polanco CM, Dien Bard J.
J Clin Microbiol. 2014 Nov;52(11):3884-9. doi: 10.1128/JCM.01489-14. Epub 2014 Aug 20. PMID: 25143573
Direct identification of bacteria from positive BacT/ALERT blood culture bottles using matrix-assisted laser desorption ionization-time-of-flight mass spectrometry.
Mestas J, Felsenstein S, Bard JD.
Diagn Microbiol Infect Dis. 2014 Nov;80(3):193-6. doi: 10.1016/j.diagmicrobio.2014.07.008. Epub 2014 Jul 31. PMID: 25139844
School-located influenza vaccination decreases laboratory-confirmed influenza and improves school attendance.
Pannaraj PS, Wang HL, Rivas H, Wiryawan H, Smit M, Green N, Aldrovandi GM, El Amin AN, Mascola L.
Clin Infect Dis. 2014 Aug 1;59(3):325-32. doi: 10.1093/cid/ciu340. Epub 2014 May 14.
Performance of the Verigene Gram-positive blood culture assay for direct detection of Gram-positive organisms and resistance markers in a pediatric hospital.
Mestas J, Polanco CM, Felsenstein S, Dien Bard J.
J Clin Microbiol. 2014 Jan;52(1):283-7. doi: 10.1128/JCM.02322-13. Epub 2013 Oct 16. PMID: 24131696
Human parechovirus central nervous system infections in southern California children.
Felsenstein S, Yang S, Eubanks N, Sobrera E, Grimm JP, Aldrovandi G.
Pediatr Infect Dis J. 2014 Apr;33(4):e87-91. doi: 10.1097/INF.0000000000000112. PMID: 24104958
Clinical and microbiologic features guiding treatment recommendations for brain abscesses in children.
Felsenstein S, Williams B, Shingadia D, Coxon L, Riordan A, Demetriades AK, Chandler CL, Bassi S, Koutoumanou E, Stapleton S, Sharland M, Bryant PA.
Pediatr Infect Dis J. 2013 Feb;32(2):129-35. doi: 10.1097/INF.0b013e3182748d6e. PMID: 23001027
Coverage of primary mother-to-child HIV transmission isolates by second-generation broadly neutralizing antibodies.
Nakamura KJ, Cerini C, Sobrera ER, Heath L, Sinkala M, Kankasa C, Thea DM, Mullins JI, Kuhn L, Aldrovandi GM.
AIDS. 2013 Jan 28;27(3):337-46. doi: 10.1097/QAD.0b013e32835cadd6.
Increased incidence of sacroiliac joint infection at a children’s hospital.
Taylor ZW1, Ryan DD, Ross LA.
J Pediatr Orthop. 2010 Dec;30(8):893-8.
Survival and transmission of community-associated methicillin-resistant Staphylococcus aureus from fomites.
Desai R, Pannaraj PS, Agopian J, Sugar CA, Liu GY, Miller LG.
Am J Infect Control. 2011 Apr;39(3):219-25. doi: 10.1016/j.ajic.2010.07.005.
The role of bronchoalveolar lavage galactomannan in the diagnosis of pediatric invasive aspergillosis.
Desai R, Ross LA, Hoffman JA.
Pediatr Infect Dis J. 2009 Apr;28(4):283-6. doi: 10.1097/INF.0b013e31818f0934.
MAJOR FEATURES OF TRAINING PROGRAM:
Our three-year program is designed to train fellows for positions in academic infectious diseases and to qualify them for subspecialty boards in pediatric infectious diseases. We provide rigorous clinical and research training. In addition, we welcome those interested in obtaining specialized training in antimicrobial stewardship, infection control, public health and global health. Children’s Hospital Los Angeles is a large free-standing children’s hospital. Fellows will be trained for inpatient and outpatient consultations on infections in both immunocompetent and immunocompromised children. Being in an urban hub, we also take care of immigrants and returned travelers from all over the world. There are additional opportunities for clinical infectious disease rotations and research in Latin America, Asia and Africa. The program includes formal training in clinical microbiology (virology, bacteriology, mycology, parasitology, and serology) as well as epidemiology, study design, biostatistics, and grant writing. Research is an integral part of the program in all three years. Fellows may work with mentors in different departments at CHLA and USC depending on their interest. Our research projects have considerable variability and include basic molecular biologic studies, translational studies, and clinical studies with supportive laboratory research. Present areas of research include studies relating to vaccines and vaccine-preventable diseases, maternal-infant microbiome, antimicrobial pharmacokinetics, epidemiology of respiratory viruses, bacterial pathogenesis, neonatal infections, infections in immunocompromised hosts, emerging infections (e.g. Ebola), global health, antibacterial stewardship, and infection control strategies.
AFFILIATED HOSPITALS: Children’s Hospital Los Angeles
NUMBER OF PEDIATRIC BEDS:347
FELLOWS ACCEPTED EACH YEAR:1 to 2
TRAINING FOR: MD, DO, MD, PhD
FUNDING ENSURED FOR ALL 3 YEARS: YES
VISAS ACCEPTED: J1, H1B
IS COMPLETION OF PEDIATRIC RESIDENCY TRAINING IN THE U.S. OR CANADA A REQUIREMENT? No
THE PROGRAM OFFERS THE FOLLOWING TRAINING: