November 10, 2022
Award celebrates contributions of Dr. Caroline B. Hall to the field of pediatric infectious diseases through innovative clinical research
Matthew Vogt, MD, PhD, a recognized research scientist, is the Pediatric Infectious Diseases Society 2022 Hall Award for Clinically Innovative Research Paper recipient. The award is presented annually to a junior or mid-career investigator who is the first or senior author of a paper that best illustrates the innovative approach to clinical research demonstrated by Dr. Caroline Hall, for whom the award is named.
Dr. Vogt studies how enterovirus D68 (EV-D68), a pathogen typically limited to the respiratory tract, causes outbreaks of acute flaccid myelitis (AFM). He identified a unique report of an autopsy from a child who died from AFM that was published years prior to large AFM outbreaks, so was not initially described in these terms. Re-examining the tissues, key aspects of EV-D68 pathogenesis were uncovered, such as specific neurotropism in motor regions of the spinal cord and a robust surrounding immune response. The results were published in May as ‘Enterovirus D68 in the Anterior Horn Cells of a Child with Acute Flaccid Myelitis’ in The New England Journal of Medicine.
“Dr. Vogt is establishing himself as a remarkably innovative investigator in our field,” said PIDS President, Dr. Buddy Creech. “His work is helping us understand the biology that underlies acute flaccid myelitis, and it provides a foundation for new diagnostics and therapeutic agents that may reduce suffering in these children.”
He is an Assistant Professor in Pediatrics (Infectious Diseases) and Microbiology & Immunology at the University of North Carolina at Chapel Hill School of Medicine. Dr. Vogt sees patients as a consultant on the Pediatric Infectious Diseases service at North Carolina Children’s Hospital and runs a basic science laboratory. It is focused on understanding why common pediatric respiratory virus infections cause severe disease in some people.
Dr. Vogt earned his degrees at Washington University in St. Louis School of Medicine. He completed a residency in pediatrics at the Boston Combined Residency Program of Boston Children’s Hospital and Boston Medical Center. Dr. Vogt then moved to Vanderbilt University Medical Center for his fellowship in Pediatric Infectious Diseases.
PIDS membership encompasses leaders across the global scientific and public health spectrum, including clinical care, advocacy, academics, government, and the pharmaceutical industry. From fellowship training to continuing medical education, research, regulatory issues and guideline development, PIDS members are the core professionals advocating for the improved health of children with infectious diseases both nationally and around the world, participating in critical public health and medical professional advisory committees that determine the treatment and prevention of infectious diseases, immunization practices in children, and the education of pediatricians. For more information, visit http://www.pids.org.